BRL 50481

CAS No. 433695-36-4

BRL 50481 ( —— )

Catalog No. M19908 CAS No. 433695-36-4

BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15 12.1 62 and 490 μM for PDE7A PDE7B PDE4 and PDE3 respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 54 In Stock
25MG 113 In Stock
50MG 203 In Stock
100MG 340 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BRL 50481
  • Note
    Research use only not for human use.
  • Brief Description
    BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15 12.1 62 and 490 μM for PDE7A PDE7B PDE4 and PDE3 respectively.
  • Description
    BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15 12.1 62 and 490 μM for PDE7A PDE7B PDE4 and PDE3 respectively.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE7
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    433695-36-4
  • Formula Weight
    244.27
  • Molecular Formula
    C9H12N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL;Ethanol: 20 mg/mL
  • SMILES
    CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
  • Chemical Name
    NN2-Trimethyl-5-nitro-benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Safavi M et al. New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurologicaland inflammatory disorders. Expert Opin Drug Discov. 2013 Jun;8(6):733-51.
molnova catalog
related products
  • Fenspiride hydrochlo...

    Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases.

  • Siguazodan

    Siguazodan is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM.

  • Lirimilast

    Lirimilast (BAY 19-8004;BAY 198004) is a potent and selective PDE4 inhibitor for the treatment of COPD.